Multiple agencies were responding to the crash, and a search-and-rescue mission was underway, according to L.A. County Supervisor Janice Hahn.

Editor's Note: This story has been updated to reflect that two people are confirmed to have died in the crash. Two people were killed, one person is missing and two were hospitalized after a medevac ...

A massive rescue effort unfolded off Catalina Island Wednesday night after a medical helicopter carrying five people plunged into more than 200 feet of water shortly after takeoff, killing three ...

Four people are recovered from the water off Catalina Island.

Add Yahoo as a preferred source to see more of our stories on Google. A helicopter with 5 people aboard crashed into the water off SoCal's Catalina Island, leaving 2 dead ... and, ironically, the ...

A medevac helicopter crashed off Catalina Island on Wednesday night, resulting in the deaths of the pilot, flight nurse, and the 45-year-old patient, Catalina Hernandez. Hernandez, a resident of the ...

A medical flight off California's coast ended in disaster Wednesday night. A medevac helicopter leaving Catalina Island for the mainland went down in the ocean around 7:53pm, reports KTLA, killing two ...

A helicopter with 5 people aboard crashed into the water off SoCal's Catalina Island, leaving 2 dead ... and, ironically, the chopper was in the middle of a mission to save a patient. Four of the ...