• Greater rigor is needed in the use of observational methods; even the best methods used incorrectly will yield bad results. (Goodman) • No one method is infallible, multiple methods are needed to ...

Standardization and reproducibility are prerequisites for peripheral blood mononuclear cell (PBMC) generation from donor or patient samples in PBMC-based studies. Whether you are analyzing ...

Protocol amendment for ENSEMBLE study: A multicenter, randomized, phase III trial to test the superiority of consolidation irinotecan, capecitabine and oxaliplatin vs capecitabine and oxaliplatin ...

Medical research is essential for advancing the understanding of health, diseases, and treatments. There are many types of studies that serve different purposes. Medical research, or health research, ...

Emerging treatments for advanced cholangiocarcinoma: Addressing the knowledge gap. Background: HCC is a leading cause of cancer-related deaths worldwide. LEN is now a first-line treatment option for ...

• Accounting for bias is a major challenge confronting the use of observational data to gain important insights into real-world treatment effects. • No single study design will satisfy all information ...