Elexacaftor-tezacaftor-ivacaftor (ETI) has transformed cystic fibrosis (CF) care for over 90% of people with CF (pwCF) in countries with access to treatment.1 Clinical trial and ‘real-world’ reports ...
Risk assessment in chronic obstructive pulmonary disease (COPD) still depends heavily on a familiar clinical shortcut: a ...
Introduction Acetazolamide improves sleep apnoea in people living at low altitude and newcomers ascending to high altitude.
Background Antibiotic therapy before presentation (prior antibiotic exposure, PAE) is reported in 11–39% of patients with ...
Systemic sclerosis (SSc) is a systemic autoimmune disease characterised by immune dysregulation and multiorgan fibrosis. 1 ...
1 Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong 2 Department of Psychiatry, Shatin Hospital, The Chinese University of Hong Kong, Shatin, ...
A 65-year-old male, who does not smoke, with a history of right lower lobectomy for carcinoid tumour 15 years prior, was referred for persistent, unexplained cough over 12 months. This was ...
PM 2.5, O 3 and survival gains from China’s clean air actions among patients with lung cancer: a 20-year registry-based cohort study in Beijing ...
BACKGROUND--Maximal inspiratory pressure (MIP) is often relied upon as an index of inspiratory muscle strength, and reproducibility of MIP taken to indicate maximal effort. This study was designed to ...
Background: Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) ...
1 Department of Paediatrics, Oxford University Hospitals NHS Trust, Oxford, UK 2 Department of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK ...
Rationale/Objectives Despite plausible pathophysiological mechanisms, research is needed to confirm the relationship between sleep, circadian rhythm and delirium in patients admitted to the intensive ...
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