A research team has discovered a new mechanism and drug combination strategy that can effectively treat osteoporosis, a ...

Researchers led by Kanazawa University show that messages sent by osteoblasts via extracellular vesicles trigger the formation of mature osteoclasts during fracture healing Kanazawa, Japan - In a ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts. This ...

Osteoporosis is the primary cause of bone fractures in the elderly, reflecting an imbalance between osteoclasts, bone-degrading cells, and osteoblasts, bone-building cells. Teriparatide is the only ...

Researchers at UC San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue — by feeding them adenosine, a naturally occurring molecule in the ...